108

Z. Ma, J. Wu, Y. Tan and C. Tan,

Azobenzene-Based Conjugated Polymers: Synthesis, Properties, and Biological Applications.

Macromolecular Rapid Communications 2024, 45, 2400048..

107

Y. Sun, L. Jiang, Z. Zhang, N. Xu, Y. Jiang and C. Tan.,

Conjugated Polyelectrolyte/Single Strand DNA Hybrid Polyplexes for Efficient Nucleic Acid Delivery and Targeted Protein Degradation.

ACS Applied Materials & Interfaces 2024, 16, 19987-19994.

106

Wang, T.; Tan, Y.; Chen, Y. Z.; Tan, C.,

Infrared Spectral Analysis for Prediction of Functional Groups Based on Feature-Aggregated Deep Learning.

Journal of Chemical Information and Modeling 2023, 63 (15), 4615-4622.

105

Jin, Y.; Sun, Y.; Du, N.; Dou, W.-T.; Tan, Y.; He, X.-P.; Xu, N.; Tan, C.,

Rapid identification of molecular subtyping of breast cancer cell lines using a multi-channel sensor array.

Sensors & Diagnostics 2023, 2 (4), 837-841.

104

Zhang, P.; Tan, C.,

Cross-Reactive Fluorescent Sensor Array for Discrimination of Amyloid Beta Aggregates.

Analytical Chemistry 2022, 94 (14), 5469-5473.

103

Jin, Y. Y.; Du, N.; Huang, Y. F.; Shen, W. X.; Tan, Y.; Chen, Y. Z.; Dou, W. T.; He, X. P.; Yang, Z. J.; Xu, N. H.; Tan, C. Y.,

Fluorescence Analysis of Circulating Exosomes for Breast Cancer Diagnosis Using a Sensor Array and Deep Learning.

ACS Sensors 2022, 7 (5), 1524-1532.

102

Chen, W. J.; Chen, H. J.; Huang, Y. R.; Tan, Y.; Tan, C. Y.; Xie, Y.; Yin, J.,

Molecular Design and Photothermal Application of Thienoisoindigo Dyes with Aggregation-Induced Emission.

ACS Applied Bio Materials 2022, 5 (7), 3428-3437.

101

Zhao, X. Y.; Du, N.; Huang, Y.; Shen, Y.; Tan, Y.; Tan, C.,

Discrimination of Powdered Infant Formula According to Species, Country of Origin, and Brand Using a Fluorescent Sensor Array.

ACS Food Science & Technology 2021, 1 (8), 1392-1398.

100

Zhao, L.; Fan, T.; Shi, Z.; Ding, C.; Zhang, C.; Yuan, Z.; Sun, Q.; Tan, C.; Chu, B.; Jiang, Y.,

Design, synthesis and evaluation of novel ErbB/HDAC multitargeted inhibitors with selectivity in EGFR(T790M) mutant cell lines.

European Journal of Medicinal Chemistry 2021, 213.

99

Wu, P.; Tan, C.,

Biological Sensing and Imaging Using Conjugated Polymers and Peptide Substrates.

Protein and Peptide Letters 2021, 28 (1), 2-10.

98

Li, J.; Du, N.; Tan, Y.; Hsu, H.-Y.; Tan, C.; Jiang, Y.,

Conjugated Polymer Nanoparticles Based on Copper Coordination for Real-Time Monitoring of pH-Responsive Drug Delivery.

ACS Applied Bio Materials 2021, 4 (3), 2583-2590.

97

Chen, J.; Jin, T.; Li, J.; Zhang, X.; Liu, F.; Tan, C.; Tan, Y.,

One-Pot Simultaneous Detection of Multiple DNA and MicroRNA by Integrating the Cationic-Conjugated Polymer and Nuclease-Assisted Cyclic Amplification.

ACS Applied Bio Materials 2021, 4 (1), 820-828.

96

Shi, H.; Jin, T.; Zhang, J.; Huang, X.; Tan, C.; Jiang, Y.; Tan, Y.,

A novel aptasensor strategy for protein detection based on G-quadruplex and exonuclease III-aided recycling amplification.

Chinese Chemical Letters 2020, 31 (1), 155-158.

95

Shen, Y.; Huang, Y.; Zhang, P.; Guo, B.; Jiang, H.; Tan, C.; Jiang, Y.,

Fluorescence Sensor Array for Discrimination of Urine Proteins and Differentiation Diagnosis of Urinary System Diseases.

ACS Applied Bio Materials 2020, 3 (9), 5639-5643.

94

Li, J.; An, Z.; Sun, J.; Tan, C.; Gao, D.; Tan, Y.; Jiang, Y.,

Highly Selective Oxidation of Organic Sulfides by a Conjugated Polymer as the Photosensitizer for Singlet Oxygen Generation.

ACS Applied Materials & Interfaces 2020, 12 (31), 35475-35481.

93

Jin, T.; Zhang, J.; Zhao, Y.; Huang, X.; Tan, C.; Sun, S.; Tan, Y.,

Magnetic bead-gold nanoparticle hybrids probe based on optically countable gold nanoparticles with dark-field microscope for T4 polynucleotide kinase activity assay.

Biosensors & Bioelectronics 2020, 150.

92

Du, N.; Tan, Y.; Zhang, C.; Tan, C.,

Poly(fluorenone-co-thiophene)-based nanoparticles for two-photon fluorescence imaging in living cells and tissues.

RSC Advances 2020, 10 (21), 12373-12377.

91

Pang, X.; Tan, Y.; Tan, C.; Li, W.; Du, N.; Lu, Y.; Jiang, Y.,

One-Step Construction of Fluorenone-Based Donor-Acceptor-Type Conjugated Polymers via Direct Arylation Polymerization for Cell-Imaging Applications.

ACS Applied Materials & Interfaces 2019, 11 (31), 28246-28253.

90

Li, S.; Gao, D.; Song, C.; Tan, C.; Jiang, Y.,

Isotope Labeling Strategies for Acylcarnitines Profile in Biological Samples by Liquid Chromatography-Mass Spectrometry.

Analytical Chemistry 2019, 91 (3), 1701-1705.

89

Huang, Y.; Cheng, P.; Tan, C.,

Visual artificial tongue for identification of various metal ions in mixtures and real water samples: a colorimetric sensor array using off-the-shelf dyes.

RSC Advances 2019, 9 (47), 27583-27587.

88

Chen, Y.; Tan, Y.; Tan, C.; Lu, Y.; Chen, Y.; Jiang, Y.,

Naphthalimide-containing conjugated polyelectrolytes with different chain configurations.

Org. Biomol. Chem. 2019, 17 (10), 2635-2639.

87

Wu, J.; Li, Y.; Tan, C.; Wang, X.; Zhang, Y.; Song, J.; Qu, J.; Wong, W.,

Aggregation-induced near-infrared emitting platinum(II) terpyridyl complex: cellular characterisation and lysosome-specific localisation.

Chemical Communications 2018, 54 (79), 11144-11147.

86

Shi, H.; Zhang, B.; Liu, S.; Tan, C.; Tan, Y.; Jiang, Y.,

A New Strategy Involving the Use of Peptides and Graphene Oxide for Fluorescence Turn-on Detection of Proteins.

Sensors 2018, 18 (2).

85

Liu, S.; Xu, N.; Tan, C.; Fang, W.; Tan, Y.; Jiang, Y.,

A sensitive colorimetric aptasensor based on trivalent peroxidase-mimic DNAzyme and magnetic nanoparticles.

Analytica Chimica Acta 2018, 1018, 86-93.

84

Liang, J.; Wu, P.; Tan, C.; Jiang, Y.,

White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation.

RSC Advances 2018, 8 (17), 9218-9222.

83

Li, A.; Tan, C.; Yuan, T.; Liang, J.; Gao, D.; Tan, Y.; Jiang, Y.,

Efficient photocatalytic oxidation sensitized by conjugated polymers in a batch reaction and microreactors under visible light.

Journal of Materials Chemistry a 2018, 6 (33), 15927-15932.

82

Fang, W.; Liu, S.; Tan, C.; Li, A.; Tan, Y.; Jiang, Y.,

Conjugated polyelectrolytes with a label-free aptamer for specific protein photoinactivation.

Analytical Methods 2018, 10 (19), 2205-2210.

81

Zhang, M.; Wu, P.; Dou, W.; Han, H.; He, X.; Tan, C.; Jiang, Y.,

Conjugated polyelectrolytes with galactose-containing side chains for targeted hepatoma cell imaging.

Chemical Communications 2017, 53 (41), 5625-5628.

80

Zhang, B.; Wang, N.; Zhang, C.; Gao, C.; Zhang, W.; Chen, K.; Wu, W.; Chen, Y.; Tan, C.; Liu, F.; Jiang, Y.,

Novel multi-substituted benzyl acridone derivatives as survivin inhibitors for hepatocellular carcinoma treatment.

European Journal of Medicinal Chemistry 2017, 129, 337-348.

79

Zhang, B.; Liu, H.; Wu, F.; Hao, G.; Chen, Y.; Tan, C.; Tan, Y.; Jiang, Y.,

A dual-response quinoline-based fluorescent sensor for the detection of Copper (II) and Iron(III) ions in aqueous medium.

Sensors and Actuators B-Chemical 2017, 243, 765-774.

78

Yuan, Z.; Sun, Q.; Li, D.; Miao, S.; Chen, S.; Song, L.; Gao, C.; Chen, Y.; Tan, C.; Jiang, Y.,

Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors.

European Journal of Medicinal Chemistry 2017, 134, 281-292.

77

Yuan, Z.; Chen, S.; Sun, Q.; Wang, N.; Li, D.; Miao, S.; Gao, C.; Chen, Y.; Tan, C.; Jiang, Y.,

Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy.

Bioorganic & Medicinal Chemistry 2017, 25 (15), 4100-4109.

76

Xue, P.; He, S.; Mao, Y.; Qu, L.; Liu, F.; Tan, C.; Jiang, Y.; Tan, Y.,

The Optimization and Characterization of an RNA-Cleaving Fluorogenic DNAzyme Probe for MDA-MB-231 Cell Detection.

Sensors 2017, 17 (3).

75

Wu, P.; Xu, N.; Tan, C.; Liu, L.; Tan, Y.; Chen, Z.; Jiang, Y.,

Light-Induced Translocation of a Conjugated Polyelectrolyte in Cells: From Fluorescent Probe to Anticancer Agent.

ACS Applied Materials & Interfaces 2017, 9 (12), 10512-10518.

74

Wu, J.; Tan, C.; Zhou, X.; Tan, Y.; Yang, P.; Jiang, Y.,

Molecular weight analysis of water-soluble poly(phenylene ethynylene)s using MALDI-TOF MS.

Journal of Polymer Science Part a-Polymer Chemistry 2017, 55 (15), 2537-2543.

73

Li, D.; Yuan, Z.; Chen, S.; Zhang, C.; Song, L.; Gao, C.; Chen, Y.; Tan, C.; Jiang, Y.,

Synthesis and biological research of novel azaacridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.

Bioorganic & Medicinal Chemistry 2017, 25 (13), 3437-3446.

72

Han, X.; Zhang, B.; Chen, J.; Liu, S.; Tan, C.; Liu, H.; Lang, M.; Tan, Y.; Liu, X.; Yin, J.,

Modulating aggregation-induced emission via a non-conjugated linkage of fluorophores to tetraphenylethenes.

Journal of Materials Chemistry B 2017, 5 (26), 5096-5100.

71

Ding, C.; Chen, S.; Zhang, C.; Hu, G.; Zhang, W.; Li, L.; Chen, Y.; Tan, C.; Jiang, Y.,

Synthesis and investigation of novel 6-(1,2,3-triazol-4-yl)-4-aminoquinazolin derivatives possessing hydroxamic acid moiety for cancer therapy.

Bioorganic & Medicinal Chemistry 2017, 25 (1), 27-37.

70

Cui, Z.; Chen, S.; Wang, Y.; Gao, C.; Chen, Y.; Tan, C.; Jiang, Y.,

Design, synthesis and evaluation of azaacridine derivatives as dual-target EGFR and Src kinase inhibitors for antitumor treatment.

European Journal of Medicinal Chemistry 2017, 136, 372-381.

69

Chen, S.; Tan, Y.; Deng, H.; Shen, Z.; Liu, Y.; Wu, P.; Tan, C.; Jiang, Y.,

UBE2J2 promotes hepatocellular carcinoma cell epithelial-mesenchymal transition and invasion in vitro.

Oncotarget 2017, 8 (42), 71736-71749.

68

Cai, K.; Tan, Y.; Tan, C.; Wu, J.; Wu, P.; Liang, J.; Liu, S.; Zhang, B.; Jiang, Y.,

An iminodiacetate-modified conjugated polyelectrolyte for fluorescent labeling of histidine-tagged proteins.

Chemical Communications 2017, 53 (30), 4191-4194.

67

Zheng, J.; Tan, C.; Xue, P.; Cao, J.; Liu, F.; Tan, Y.; Jiang, Y.,

Proteolysis targeting peptide (PROTAP) strategy for protein ubiquitination and degradation.

Biochemical and Biophysical Research Communications 2016, 470 (4), 936-940.

66

Zhang, W.; Zhang, B.; Yang, T.; Wang, N.; Gao, C.; Tan, C.; Liu, H.; Jiang, Y.,

Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.

European Journal of Medicinal Chemistry 2016, 116, 59-70.

65

Lv, Y.; Wu, J.; Wu, P.; Chen, Y.; Tan, Y.; Tan, C.; Jiang, Y.,

A sensitive polymeric dark quencher-based sensing platform for fluorescence “turn on” detection of proteins.

RSC Advances 2016, 6 (48), 42443-42446.

64

Liu, Y.; Wu, P.; Jiang, J.; Wu, J.; Chen, Y.; Tan, Y.; Tan, C.; Jiang, Y.,

Conjugated Polyelectrolyte Nanoparticles for Apoptotic Cell Imaging.

ACS Applied Materials & Interfaces 2016, 8 (34), 21984-21989.

63

Liu, H.; Zhang, B.; Tan, C.; Liu, F.; Cao, J.; Tan, Y.; Jiang, Y.,

Simultaneous bioimaging recognition of Al3+ and Cu2+ in living-cell, and further detection of F- and S2- by a simple fluorogenic benzimidazole-based chemosensor.

Talanta 2016, 161, 309-319.

62

Liu, H.; Wu, F.; Zhang, B.; Tan, C.; Chen, Y.; Hao, G.; Tan, Y.; Jiang, Y.,

A simple quinoline-derived fluorescent sensor for the selective and sequential detection of copper(II) and sulfide ions and its application in living-cell imaging.

RSC Advances 2016, 6 (81), 77508-77514.

61

Liu, H.; Dong, Y.; Zhang, B.; Liu, F.; Tan, C.; Tan, Y.; Jiang, Y.,

An efficient quinoline-based fluorescence sensor for zinc(II) and its application in live-cell imaging.

Sensors and Actuators B-Chemical 2016, 234, 616-624.

60

Dou, W.; Zhang, Y.; Lv, Y.; Wu, J.; Zang, Y.; Tan, C.; Li, J.; Chen, G.; He, X.,

Interlocked supramolecular glycoconjugated polymers for receptor-targeting theranostics.

Chemical Communications 2016, 52 (19), 3821-3824.

59

Dou, W.; Zeng, Y.; Lv, Y.; Wu, J.; He, X.; Chen, G.; Tan, C.,

Supramolecular Ensembles Formed between Charged Conjugated Polymers and Glycoprobes for the Fluorogenic Recognition of Receptor Proteins.

ACS Applied Materials & Interfaces 2016, 8 (21), 13601-13606.

58

Dou, W.; Lv, Y.; Tan, C.; Chen, G.; He, X.,

Irreversible destruction of amyloid fibril plaques by conjugated polymer based fluorogenic nanogrenades.

Journal of Materials Chemistry B 2016, 4 (26), 4502-4506.

57

Cui, Z.; Li, X.; Li, L.; Zhang, B.; Gao, C.; Chen, Y.; Tan, C.; Liu, H.; Xie, W.; Yang, T.; Jiang, Y.,

Design, synthesis and evaluation of acridine derivatives as multi-target Src and MEK kinase inhibitors for anti-tumor treatment.

Bioorganic & Medicinal Chemistry 2016, 24 (2), 261-269.

56

Chen, C.; Liu, H.; Zhang, B.; Wang, Y.; Cai, K.; Tan, Y.; Gao, C.; Liu, H.; Tan, C.; Jiang, Y.,

A simple benzimidazole quinoline-conjugate fluorescent chemosensor for highly selective detection of Ag+.

Tetrahedron 2016, 72 (27-28), 3980-3985.

55

Zhang, B.; Chen, K.; Wang, N.; Gao, C.; Sun, Q.; Li, L.; Chen, Y.; Tan, C.; Liu, H.; Jiang, Y.,

Molecular design, synthesis and biological research of novel pyridyl acridones as potent DNA-binding and apoptosis-inducing agents.

European Journal of Medicinal Chemistry 2015, 93, 214-226.

54

Wu, Y.; Tan, Y.; Wu, J.; Chen, S.; Chen, Y.; Zhou, X.; Jiang, Y.; Tan, C.,

Fluorescence Array-Based Sensing of Metal Ions Using Conjugated Polyelectrolytes.

ACS Applied Materials & Interfaces 2015, 7 (12), 6882-6888.

53

Tao, L.; Zhu, F.; Qin, C.; Zhang, C.; Chen, S.; Zhang, P.; Zhang, C.; Tan, C.; Gao, C.; Chen, Z.; Jiang, Y.; Chen, Y.,

Clustered Distribution of Natural Product Leads of Drugs in the Chemical Space as Influenced by the Privileged Target-Sites.

Scientific Reports 2015, 5.

52

Li, L.; Shen, W.; Zheng, J.; Lai, R.; Tan, C.; Tan, Y.; Jiang, Y.,

Mutation of the conserved GRG motif and decreasing activity of human RNase H2.

Open Life Sciences 2015, 10 (1), 322-327.

51

Gao, C.; Li, B.; Zhang, B.; Sun, Q.; Li, L.; Li, X.; Chen, C.; Tan, C.; Liu, H.; Jiang, Y.,

Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents.

Bioorganic & Medicinal Chemistry 2015, 23 (8), 1800-1807.

50

Li, B.; Gao, C.-M.; Sun, Q.-S.; Li, L.-L.; Tan, C.-Y.; Liu, H.-X.; Jiang, Y.-Y.,

Novel synthetic acridine-based derivatives as topoisomerase I inhibitors.

Chinese Chemical Letters 2014, 25 (7), 1021-1024.

49

Ding, C.; Zhang, C.; Zhang, M.; Chen, Y.; Tan, C.; Tan, Y.; Jiang, Y.,

Multitarget inhibitors derived from crosstalk mechanism involving VEGFR2.

Future Medicinal Chemistry 2014, 6 (16), 1771-1789.

48

Zeng, X.; Tao, W.; Mei, L.; Huang, L.; Tan, C.; Feng, S.,

Cholic acid-functionalized nanoparticles of star-shaped PLGA-vitamin E TPGS copolymer for docetaxel delivery to cervical cancer.

Biomaterials 2013, 34 (25), 6058-6067.

47

Wu, J.; Tan, Y.; Xie, Y.; Wu, Y.; Zhao, R.; Jiang, Y.; Tan, C.,

Diazobenzene-containing conjugated polymers as dark quenchers.

Chemical Communications 2013, 49 (97), 11379-11381.

46

Wang, Y.; Wang, R.; Jiang, Y.; Tan, C.; Fu, H.,

Copper-Catalyzed Domino Synthesis of 4-Oxopyrimido[1,2-a]indole Derivatives.

Adv. Synth. Catal. 2013, 355 (14-15), 2928-2935.

45

Liu, R.; Tan, Y.; Zhang, C.; Wu, J.; Mei, L.; Jiang, Y.; Tan, C.,

A real-time fluorescence turn-on assay for trypsin based on a conjugated polyelectrolyte.

Journal of Materials Chemistry B 2013, 1 (10), 1402-1405.

44

Lang, X.; Li, L.; Chen, Y.; Sun, Q.; Wu, Q.; Liu, F.; Tan, C.; Liu, H.; Gao, C.; Jiang, Y.,

Novel synthetic acridine derivatives as potent DNA-binding and apoptosis-inducing antitumor agents.

Bioorganic & Medicinal Chemistry 2013, 21 (14), 4170-4177.

43

Jin, F.; Gao, D.; Zhang, C.; Liu, F.; Chu, B.; Chen, Y.; Chen, Y.; Tan, C.; Jiang, Y.,

Exploration of 1-(3-chloro-4-(4-oxo-4H-chromen-2-yl)phenyl)-3-phenylurea derivatives as selective dual inhibitors of Raf1 and JNK1 kinases for anti-tumor treatment.

Bioorganic & Medicinal Chemistry 2013, 21 (3), 824-831.

42

Jin, F.; Gao, D.; Wu, Q.; Liu, F.; Chen, Y.; Tan, C.; Jiang, Y.,

Exploration of N-(2-aminoethyl)piperidine-4-carboxamide as a potential scaffold for development of VEGFR-2, ERK-2 and Abl-1 multikinase inhibitor.

Bioorganic & Medicinal Chemistry 2013, 21 (18), 5694-5706.

41

Zhu, F.; Ma, X.; Qin, C.; Tao, L.; Liu, X.; Shi, Z.; Zhang, C.; Tan, C.; Chen, Y.; Jiang, Y.,

Drug Discovery Prospect from Untapped Species: Indications from Approved Natural Product Drugs.

Plos One 2012, 7 (7).

40

Zhao, R.; Xie, Y.; Tan, Y.; Tan, C.; Jiang, Y.,

Binding of a bcl-2 Family Inhibitor to Bovine Serum Albumin: Fluorescence Quenching and Molecular Docking Study.

Protein and Peptide Letters 2012, 19 (9), 949-954.

39

Zhang, X.; Tan, Y.; Zhao, R.; Chu, B.; Tan, C.; Jiang, Y.,

Site-directed Mutagenesis Study of the Ile140 in Conserved Hydrophobic Core of Bcl-x(L).

Protein and Peptide Letters 2012, 19 (9), 991-996.

38

Zhang, J.; Jia, J.; Zhu, F.; Ma, X.; Han, B.; Wei, X.; Tan, C.; Jiang, Y.; Chen, Y.,

Analysis of bypass signaling in EGFR pathway and profiling of bypass genes for predicting response to anticancer EGFR tyrosine kinase inhibitors.

Molecular Biosystems 2012, 8 (10), 2645-2656.

37

Zhang, J.; Han, B.; Wei, X.; Tan, C.; Chen, Y.; Jiang, Y.,

A Two-Step Target Binding and Selectivity Support Vector Machines Approach for Virtual Screening of Dopamine Receptor Subtype-Selective Ligands.

Plos One 2012, 7 (6).

36

Zhang, C.; Tan, C.; Ding, H.; Xin, T.; Jiang, Y.,

Selective VEGFR Inhibitors for Anticancer Therapeutics in Clinical Use and Clinical Trials.

Current Pharmaceutical Design 2012, 18 (20), 2921-2935.

35

Xie, Y.; Zhao, R.; Tan, Y.; Zhang, X.; Liu, F.; Jiang, Y.; Tan, C.,

Conjugated Polymer-Based Real-Time Fluorescence Caspase Assays.

ACS Applied Materials & Interfaces 2012, 4 (1), 405-410.

34

Xie, Y.; Tan, Y.; Liu, R.; Zhao, R.; Tan, C.; Jiang, Y.,

Continuous and Sensitive Acid Phosphatase Assay Based on a Conjugated Polyelectrolyte.

ACS Applied Materials & Interfaces 2012, 4 (8), 3784-3787.

33

Shi, Z.; Ma, X.; Qin, C.; Jia, J.; Jiang, Y.; Tan, C.; Chen, Y.,

Combinatorial support vector machines approach for virtual screening of selective multi-target serotonin reuptake inhibitors from large compound libraries.

Journal of Molecular Graphics & Modelling 2012, 32, 49-66.

32

Han, B.; Ma, X.; Zhao, R.; Zhang, J.; Wei, X.; Liu, X.; Liu, X.; Zhang, C.; Tan, C.; Jiang, Y.; Chen, Y.,

Development and experimental test of support vector machines virtual screening method for searching Src inhibitors from large compound libraries.

Chemistry Central Journal 2012, 6.

31

Gao, C.; Li, S.; Lang, X.; Liu, H.; Liu, F.; Tan, C.; Jiang, Y.,

Synthesis and evaluation of 10-(3,5-dimethoxy)benzyl-9(10H)-acridone derivatives as selective telomeric G-quadruplex DNA ligands.

Tetrahedron 2012, 68 (38), 7920-7925.

30

Ding, H.; Chen, Z.; Zhang, C.; Xin, T.; Wang, Y.; Song, H.; Jiang, Y.; Chen, Y.; Xu, Y.; Tan, C.,

Synthesis and Cytotoxic Activity of Some Novel N-Pyridinyl-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide Derivatives.

Molecules 2012, 17 (4), 4703-4716.

29

Zu, X.; Ma, J.; Liu, H.; Liu, F.; Tan, C.; Yu, L.; Wang, J.; Xie, Z.; Cao, D.; Jiang, Y.,

Pro-oncogene Pokemon promotes breast cancer progression by upregulating survivin expression.

Breast Cancer Research 2011, 13 (2).

28

Zhu, F.; Qin, C.; Tao, L.; Liu, X.; Shi, Z.; Ma, X.; Jia, J.; Tan, Y.; Cui, C.; Lin, J.; Tan, C.; Jiang, Y.; Chen, Y.,

Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting.

Proceedings of the National Academy of Sciences of the United States of America 2011, 108 (31), 12943-12948.

27

Zhao, R.; Tan, C.; Xie, Y.; Gao, C.; Liu, H.; Jiang, Y.,

One step synthesis of azo compounds from nitroaromatics and anilines.

Tetrahedron Letters 2011, 52 (29), 3805-3809.

26

Zhang, C.; Tan, C.; Zu, X.; Zhai, X.; Liu, F.; Chu, B.; Ma, X.; Chen, Y.; Gong, P.; Jiang, Y.,

Exploration of (S)-3-aminopyrrolidine as a potentially interesting scaffold for discovery of novel Abl and PI3K dual inhibitors.

European Journal of Medicinal Chemistry 2011, 46 (4), 1404-1414.

25

Wei, X.; Han, B.; Zhang, J.; Liu, X.; Tan, C.; Jiang, Y.; Low, B.; Tidor, B.; Chen, Y.,

An Integrated Mathematical Model of Thrombin-, Histamine-and VEGF-Mediated Signalling in Endothelial Permeability.

BMC Systems Biology 2011, 5.

24

Luan, X.; Gao, C.; Zhang, N.; Chen, Y.; Sun, Q.; Tan, C.; Liu, H.; Jin, Y.; Jiang, Y.,

Exploration of acridine scaffold as a potentially interesting scaffold for discovering novel multi-target VEGFR-2 and Src kinase inhibitors.

Bioorganic & Medicinal Chemistry 2011, 19 (11), 3312-3319.

23

Luan, X.; Gao, C.; Sun, Q.; Tan, C.; Liu, H.; Jin, Y.; Jiang, Y.,

Novel Synthetic Azaacridine Analogues as Topoisomerase 1 Inhibitors.

Chem. Lett. 2011, 40 (7), 728-729.

22

Li, Y.; Tan, C.; Gao, C.; Zhang, C.; Luan, X.; Chen, X.; Liu, H.; Chen, Y.; Jiang, Y.,

Discovery of benzimidazole derivatives as novel multi-target EGFR, VEGFR-2 and PDGFR kinase inhibitors.

Bioorganic & Medicinal Chemistry 2011, 19 (15), 4529-4535.

21

Hu, X.; Gao, C.; Tan, C.; Zhang, C.; Zhang, H.; Li, S.; Liu, H.; Jiang, Y.,

Design and Synthesis of N-phosphoryl Peptide Modified Podophyllotoxin Derivatives as Potent Anticancer Agents.

Protein and Peptide Letters 2011, 18 (12), 1258-1264.

20

Tan, C.; Xie, Y.; He, X.; Wang, K.; Jiang, Y.,

Hyper-Efficient Quenching of a Conjugated Polyelectrolyte by Dye-Doped Silica Nanoparticles: Better Quenching in the Nonaggregated State.

Langmuir 2010, 26 (3), 1528-1532.

19

Ma, X.; Wang, R.; Tan, C.; Jiang, Y.; Lu, T.; Rao, H.; Li, X.; Go, M.; Low, B.; Chen, Y.,

Virtual Screening of Selective Multitarget Kinase Inhibitors by Combinatorial Support Vector Machines.

Molecular Pharmaceutics 2010, 7 (5), 1545-1560.

18

Ma, X.; Shi, Z.; Tan, C.; Jiang, Y.; Go, M.; Low, B.; Chen, Y.,

In-Silico Approaches to Multi-target Drug Discovery.

Pharmaceutical Research 2010, 27 (5), 739-749.

17

Liu, H.; Dong, A.; Gao, C.; Tan, C.; Xie, Z.; Zu, X.; Qu, L.; Jiang, Y.,

New synthetic flavone derivatives induce apoptosis of hepatocarcinoma cells.

Bioorganic & Medicinal Chemistry 2010, 18 (17), 6322-6328.

16

Huang, Q.; Tan, C.; Jiang, Y.,

Small Molecule Mimics of alpha-Helix.

Progress in Chemistry 2010, 22 (1), 101-106.

15

Gao, C.; Liu, F.; Luan, X.; Tan, C.; Liu, H.; Xie, Y.; Jin, Y.; Jiang, Y.,

Novel synthetic 2-amino-10-(3,5-dimethoxy)benzyl-9(10H)-acridinone derivatives as potent DNA-binding antiproliferative agents.

Bioorganic & Medicinal Chemistry 2010, 18 (21), 7507-7514.

14

Zhang, N.; Tan, C.; Cai, P.; Zhang, P.; Zhao, Y.; Jiang, Y.,

The design, synthesis and evaluation of hypoxia-activated pro-oligonucleotides.

Chemical Communications 2009, (22), 3216-3218.

13

Zhang, N.; Tan, C.; Cai, P.; Zhang, P.; Zhao, Y.; Jiang, Y.,

RNA interference in mammalian cells by siRNAs modified with morpholino nucleoside analogues.

Bioorganic & Medicinal Chemistry 2009, 17 (6), 2441-2446.

12

Liu, X. H.; Ma, X. H.; Tan, C. Y.; Jiang, Y. Y.; Go, M. L.; Low, B. C.; Chen, Y. Z.,

Virtual Screening of Abl Inhibitors from Large Compound Libraries by Support Vector Machines.

Journal of Chemical Information and Modeling 2009, 49 (9), 2101-2110.

11

Zhang, N.; Tan, C.; Cai, P.; Jiang, Y.; Zhang, P.; Zhao, Y.,

Synthesis and properties of morpholino chimeric oligonucleotides.

Tetrahedron Letters 2008, 49 (22), 3570-3573.

10

Yu, X.; Tan, C.; Zhang, N.; Xu, W.; Jiang, Y.,

Synthesis and biological evaluation of N-phosphoryl dipeptide derivatives as potent apoptosis inducers.

Protein and Peptide Letters 2008, 15 (4), 356-359.

9

Liu, H.; Dong, A.; Gao, C.; Tan, C.; Liu, H.; Zu, X.; Jiang, Y.,

The design, synthesis, and anti-tumor mechanism study of N-phosphoryl amino acid modified resveratrol analogues.

Bioorganic & Medicinal Chemistry 2008, 16 (23), 10013-10021.

8

Gao, C.-M.; Liu, H.-C.; Jiang, Y.-Y.; Tan, C.-Y.; Cao, D.-R.,

Synthesis of 10-Benzyl-9-acridone and Its Reduction with NaBH4.

Chinese Journal of Organic Chemistry 2008, 28 (10), 1803-1806.

7

Gao, C.; Jiang, Y.; Tan, C.; Zu, X.; Liu, H.; Cao, D.,

Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones.

Bioorganic & Medicinal Chemistry 2008, 16 (18), 8670-8675.

6

Pinto, M.; Tan, C.; Ramey, M.; Reynolds, J.; Bergstedt, T.; Whitten, D.; Schanze, K.,

Amplified fluorescence quenching and biosensor application of a poly(para-phenylene) cationic polyelectrolyte.

Research on Chemical Intermediates 2007, 33 (1-2), 79-90.

5

Ramey, M.; Hiller, J.; Rubner, M.; Tan, C.; Schanze, K.; Reynolds, J.,

Amplified fluorescence quenching and electroluminescence of a cationic poly(p-phenylene-co-thiophene) polyelectrolyte.

Macromolecules 2005, 38 (2), 234-243.

4

Tan, C.; Pinto, M.; Kose, M.; Ghiviriga, I.; Schanze, K.,

Solvent-induced self-assembly of a meta-linked conjugated polyelectrolyte. Helix formation, guest intercalation, and amplified quenching.

Advanced Materials 2004, 16 (14), 1208-+.

3

Tan, C.; Alas, E.; Muller, J.; Pinto, M.; Kleiman, V.; Schanze, K.,

Amplified quenching of a conjugated polyelectrolyte by cyanine dyes.

Journal of the American Chemical Society 2004, 126 (42), 13685-13694.

2

Haskins-Glusac, K.; Pinto, M.; Tan, C.; Schanze, K.,

Luminescence quenching of a phosphorescent conjugated polyelectrolyte.

Journal of the American Chemical Society 2004, 126 (45), 14964-14971.

1

Tan, C.; Pinto, M.; Schanze, K.,

Photophysics, aggregation and amplified quenching of a water-soluble poly( phenylene ethynylene).

Chemical Communications 2002, (5), 446-447.